All flights have been re-routed to the airport's backup runway, setting of delays and cancellations for some travellers.
Gatiwkc Airport has ground to a standstill after the Toronto-bound Air Canada flight hit debris on the runway which burst its wheels on take-off at around 1pm.
"Following this Gatwick's runway has been closed since 2.12pm to allow for a runway inspection".
"There are some delays for the time being, and we expect we may see some cancellations today".
An airline spokesman said: "Air Canada Rouge flight 1925 Gatwick-Toronto, a Boeing 767 with 282 passengers on board, landed safely back at Gatwick".
"We apologise as flights for the rest of the day will experience delay and there will be some cancellations", the statement said.
Gatwick Airport authorities urged all passengers to check with their airlines for more flight information.
"As per standard operation procedures and as a precautionary measure the crew requested emergency services presence after a tyre blew upon take-off".