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Arsenal are likely to recall a host of first-team regulars for the short trip to face the Premier League champions.
The Blues have gone on to get wins over Tottenham Hotspur, Everton and Leicester City, however no performance was more impressive than their last.
Pedro, Davide Zappacosta Cesar Azpilicueta, Tiemoue Bakayoko and Michy Batshuayi all found the net for their side.
Former Arsenal man Paul Merson has made no secret of his dissatisfaction with the way the Gunners have been performing in recent times, but ahead of Sunday's clash between Wenger's men and Chelsea he has hammered home just how much of gulf in class there is between the two squads.
He said: "I'm the type of guy that when I'm told I can't play under this type of manager, not with his style, if you tell me this some fire comes inside me, and I want to prove everyone wrong".
These include a loss away to Stoke City and a 4-nil thrashing at the hands of Liverpool.
The England worldwide has started in our last two encounters with the Blues, in which we came away with wins in the FA Cup final and Community Shield, and Merson believes he is key in hurting today's opponents.
"You say "Arsenal beat them at the Emirates, they beat them in the FA Cup".
The Chilean, who was on the verge of joining Manchester City on transfer deadline day, was the star of the Europa League game against Cologne and scored a superb victor. If not, expect Chelsea to run them over.