"September was the deadliest month of 2017 for civilians with daily reports of attacks on residential areas resulting in hundreds of conflict-related deaths and injuries", United Nations regional humanitarian co-ordinator Panos Moumtzis said in a statement.
Wednesday, October 4, in Syria a Russian air strike killed 38 civilians.
Members of the Syrian Democratic Forces on the eastern frontline of Raqqa.
This week, airstrikes on Ar-Raqqa city killed dozens of people and injured many others. The humanitarian crisis is this area was further aggravated by the attacks on a number of medical facilities.
The U.S. -led coalition fighting ISIS has carried out airstrikes that have also caused civilian casualties, which it says it goes to great lengths to avoid.
"Targeting of civilians and facilities including hospitals and other medical facilities is simply unacceptable and constitute a grave violation of human rights and worldwide humanitarian law and may amount to war crimes", Moumtzis concluded, expressing praise for the "phenomenal work carried out by humanitarian workers and in particular national staff".
The International Committee of the Red Cross (ICRC) said in a statement that up to 10 hospitals were reported to have been damaged in the past 10 days.
ICRC says the violence is not only taking place in Raqqa - one of the few remaining ISIS strongholds - but also in Deir Ezzor, and western rural Aleppo, but also in numerous de-escalation areas, such as Idleb, rural Hama and Eastern Ghouta.
"While recent months had provided some reasons to be hopeful, the return to violence is once again bringing intolerable levels of suffering to wide areas of the country, while at the same time decreasing access for humanitarian agencies", added Gasser.
As more people are fleeing from the violence, ICRC says some camps around Raqqa and Deir Ezzor are receiving more than 1,000 women, children and men every day and humanitarian organizations are struggling to provide water, food and basic hygiene to the new arrivals.