"There will be no ability to fight fire in these kinds of winds", Pimlott said.
In Los Angeles County, firefighters responded to threats on multiple fronts.
The Southern California wildfires spreading through Ventura and Los Angeles counties are among the devastating wildfires residential communities have seen in the decades since developers have expanded further and further onto land prone to natural disaster.
Heavy winds could also cause the smaller fires in Bel-Air, Sylmar and Santa Clarita to grow more.
Officials were concerned about part of the Thomas fire heading northeast and threatening a nursing home in Ojai.
Those conditions continued through much of Tuesday, as the fire swept through neighborhoods, destroying hundreds of homes.
The blaze, which was reported at 4:52 a.m. Wednesday on the east side of the San Diego (405) Freeway near Mulholland Drive and prompted a morning rush hour closure of the freeway in the Sepulveda Pass, was estimated to have scorched at least 475 acres, Hogan said.
The University of California, Los Angeles cancelled classes - two days before the start of final exams - as firefighters battled the "Skirball" fire near the sprawling campus.
Of the blazes that had already been burning, the largest and most active was the Thomas fire that burned more than 150 structures earlier this week, was marching along the coastline north of the city of Ventura.
The canyons can accelerate fires, McLean said.
Los Angeles Mayor Eric Garcetti said over 230,000 people have been forced to evacuate in Los Angeles and Ventura counties.
The fire was only 5 percent contained as of Wednesday night.
Police knocked on doors and used loudspeakers to make sure everybody had left their homes.
Mr Murdoch said in a statement: "The property was evacuated but based on what we are seeing on TV there may be damage to some buildings in the upper vineyard area. Lord 'Be still, '" one Twitter user wrote. "Thinking of everyone else affected and continuing my lifelong intense love of firefighters", she added.
The Getty - home to masterpieces including works by Monet and Rembrandt - was closed.
The acclaimed Getty arts institution - home to masterpieces including "The Spring" by Edouard Manet - was closed until at least Thursday, with museum authorities tweeting that "air filtration systems are protecting the galleries from smoke".
This has been California's deadliest year ever for wildfires.