Almost every celebrity wore black in support of Times Up - a legal defense fund for sexual harassment victims.
Also nominated from the film were Greta Gerwig for Best Screenplay and Laurie Metcalf for Best Supporting Actress, but they lost out to Three Billboards Outside Ebbing Missouri's Martin McDonagh and I, Tonya's Allison Janney, respectively.
Gary Oldman was named best drama movie actor for his role as British wartime leader Winston Churchill in "Darkest Hour" and Frances McDormand took home the award for drama actress for her role as an angry mother seeking vengeance in "Three Billboards".
"But their time is up", she added, earning a standing ovation."I want all the girls watching here and now to know that a new day is on the horizon", she added.
Yes, there were a bunch of awards given out last night in Hollywood at the 75th Annual Golden Globes, but who won what took a back seat to who said what, as the evening was punctuated with passionate and heartfelt speeches from women praising and championing the #MeToo movement and Time's Up initiative.
The HBO TV series was one of several female-driven winners on Sunday.
McDormand was again bleeped when she spoke of the "tectonic shift" in Hollywood that has seen the treatment of women thrust into the spotlight.
"The Marvelous Mrs. Maisel", Amazon's show about a 1950s housewife trying to embark on a comedy career, won the prize for best comedy series.
-Series, Drama - "The Handmaid's Tale".
-Actor, Series, Musical or Comedy: Aziz Ansari, "Master of None".
The show's star, Rachel Brosnahan, won her first career Golden Globe for lead actress in a comedy. "Thank you for making this the greatest experience of my career". "May we teach our children that speaking out without the fear of retribution is our culture's new North Star".
Based on the novel by André Aciman, Call Me By Your Name tells the story of Elio (Timothée Chalamet) who falls in love with Oliver, (Armie Hammer), an American academic who comes to stay at his family's home in Italy during the summer of 1983. Earlier in the night, Alexandre Desplat was honored with the Best Original Score award for his work on the sci-fi movie.