One of the victims, named as Shane Gilmer, died yesterday morning, police confirmed, with a flood of heartfelt tributes now being paid to the 30-year-old on social media.
Extensive searches are underway to locate Anthony Lawrence who police want speak to urgently in connection with a suspected murder in Southburn, Driffield.
A murder inquiry had been launched after an alleged attack in the village of Southburn near Driffield on Friday night, with a man and a woman taken to hospital in Hull.
Police thanked the public for help in tracing Mr Lawrence's blue Vauxhall Meriva following an appeal. "Call us on 999".
Chief inspector Andy Parsons from Humberside Police said: 'At this point it is believed that this was an isolated incident and there is no threat to the wider public'. The woman is said to be in a stable condition.
According to reports, a crossbow was used in the attack and police have cordoned off the rural village and have been searching local woods.
"The man's family is being supported by specialist officers".
East Riding of Councillor for the Southburn area, Felicity Temple said: 'We don't know anything, but the police helicopter has been flying overhead.
The force has issued an appeal to find the suspect, 55-year-old Anthony Lawrence, and officers have found his vehicle abandoned.
He added: 'Anthony, it's vital that we speak to you about this incident as soon as possible and I would urge you to go straight to your nearest police station so that we can do this.
If you believe you have seen Mr Lawrence or this vehicle, please do not approach him yourself.
'Avoiding speaking to us could only make matters worse for you in the long run'.
Mr Lawrence is described as being white, in his late 40s, around five foot 10 inches tall, balding, with close cropped dark hair and large build.