Gregor Townsend has made five changes to his starting line-up to face Italy for Scotland's final match of the 2018 NatWest 6 Nations campaign in Rome.
Wing Tommy Seymour, centre Nick Grigg, hooker Fraser Brown, prop Willem Nel and lock Tim Swinson have all been called in to start against the Azzurri in Rome with Blair Kinghorn, Pete Horne, Stuart McInally, Simon Berghan and Grant Gilchrist the players to make way.
McInally is retained in the match-day 23 with a place on the bench, while new squad additions Richie Gray and Zander Fagerson are poised to feature for the first time in the campaign, having recovered from their respective calf and foot ailments.
Italy are bottom of the table, without a Six Nations win since their visit to Murrayfield in 2015.
Scotland's title hopes came to a crushing end when defeated 28-8 to Ireland in Dublin last week, raising further concerns regarding their away form - and a feeling of disappointment emerging given their failure to build upon their Calcutta Cup victory over England.
"There were a number of positives in how we took the game to Ireland in attack and defence but this didn't lead to us scoring enough points to win the game".
"Playing Italy will be a very tough game - it always has been for any Scotland side".
Townsend's reign as head coach began with a 34-13 victory against Italy in Singapore last June.
Ireland have already been crowned Six Nations champions this year, but Scotland could finish second if results go their way.