And former Arsenal star Merson is backing both of the teams to share the spoils in an uninteresting goalless draw in the Premier League opener.
With the game only eight minutes old, Vertonghen, fresh from Belgium's third-placed World Cup finish, gave the visitors the lead when his header against the underside of the crossbar was adjudged to have crossed the line by goal-line technology.
The Magpies are preparing to welcome the north London club to St James' Park as they look to try and get the new campaign off to a positive start under Rafael Benitez.
"I told them yesterday for me it's like we start from zero", Spurs manager Pochettino said.
But Newcastle levelled shortly after through Joselu, ghosting in-between Spurs defenders before heading home Ritchie's wonderful ball from the right flank.
The Denmark worldwide delivered the resulting corner for defender Davinson Sanchez to attack.
With Chelsea, Man City and Arsenal following that match, failing to get something on the day out in Wales could leave us looking at a grim position come mid-September. Newcastle walks away with the loss and an injury as DeAndre Yedlin left late with an apparent knee injury.
Newcastle brought on Rondon with half an hour remaining, and he almost grabbed a point in the closing stages, seeing his effort deflect off Vertonghen and onto the bar.
The "Neptune Green" colour, which Harry Kane & Co. will be sporting a few times this term, is inspired by "the original Charrington's Brewery logo, the company that originally owned part of the land where the new Tottenham Hotspur Stadium has been built", according to a news release. You know me. It's not because they were at the World Cup that they are going to play in the team.
Pochettino handed a debut to academy graduate Luke Amos, bringing him on for the "tired" Dier.