Mind has collaborated with The Royal Foundation, Heads Together and 11 other organisations and created an online portal to help both employees and employers with advice and information.
The survey of more than 44,000 employees also revealed that only half of those who had experienced poor mental health had talked to their employer about it, suggesting that as many as one in four United Kingdom workers is struggling in silence.
Following his Heads Together campaign in partnership with the Duchess of Cambridge and the Duke of Sussex, the royal launches his new initiative to change the way United Kingdom employers look at mental health in the workplace.
The research comes just days after the Yorkshire Post revealed the increasing toll on the mental health of the region's emergency workers. This results in an average of 24 days lost per worker.
The Duke of Cambridge was in attendance at an event in Bristol today.
The Duke will be joined at Tuesday's launch by Antonio Horta-Osorio, chief executive of Lloyds Banking Group.
He said: "I took a lot home without realising it".
"As employers, we have a real opportunity to change the way we approach mental health, giving our people the support they need to thrive".
A recent poll by the Institute of Directors found less than one in five firms offered mental health training for managers.
25%: This is the year-on-year increase of the number of days taken off work because of mental health issues.
"People spend more time there than nearly anywhere else, yet research shows that it's also the place where we're least comfortable talking about mental health".
Farmer added on the dedication that not just Prince William, but all the Royals, have to mental health awareness: "My firm belief is that all of [the royals] and particularly the Duke - in this context - have done a lot of background work and really thought about this issue and their commitment is 100 per cent real".
Half of all employees are impacted by poor mental health.